bsm-52216R [Primary Antibody]
PI 3 Kinase p85 alpha (2G4) Monoclonal Antibody
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: PI 3 Kinase p85 alpha

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 5295

Swiss Prot: P27986

Source: Recombinant human PI 3 Kinase p85 alpha protein, around 600-700aa.

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. Store at -20°C for 12 months.

Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:1000-2000)
IF(ICC)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.