Target Protein: Histone H2A.Z
Entrez Gene: 3012
Swiss Prot: P04908
Source: Recombinant human Histone H2A.Z protein, around 1-100aa.
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. Store at -20°C for 12 months.
Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.