bs-50553R [Primary Antibody]
14-3-3 beta Polyclonal Antibody
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Host: Rabbit

Target Protein: 14-3-3 beta

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7529

Swiss Prot: P31946

Source: Recombinant human protein purified from E.coli

Storage: HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Store for 1 year at -20°C from date of shipment.

Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.

Size: 100ul

Applications: WB(1:500-2000)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.