bs-3000R-Biotin [Conjugated Primary Antibody]
14-3-3 zeta / delta (Ser58) Antibody, Biotin Conjugated
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Host: Rabbit

Target Protein: 14-3-3 zeta / delta Ser58

Specificity: This antibody will react with all 14-3-3 proteins containing the conserved motif RS(S-p)WR.

Immunogen Range: 30-70/245

Modification Site: Ser58

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7534, 7529, 10971

Source: KLH conjugated synthetic phosphopeptide derived from human 14-3-3 protein zeta/delta around the phosphorylation site of Ser58 [RS(p-S)WR]

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
IHC-P(1:200-400)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.