Target Protein: CCR5/CD195
Immunogen Range: 204-233/352
Entrez Gene: 1234
Swiss Prot: P51681
Source: KLH conjugated synthetic peptide derived from human CCR-5
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Background: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.