bs-1634R [Primary Antibody]
ATF6 Polyclonal Antibody
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Host: Rabbit

Target Protein: ATF6

Immunogen Range: 300-350/670

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 22926

Swiss Prot: P18850

Source: KLH conjugated synthetic peptide derived from human ATF6

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

Background: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat brain labeled with Anti-ATF6 Polyclonal Antibody, Unconjugated (bs-1634R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Mouse pancreas lysates probed with ATF6 Polyclonal Antibody, unconjugated (bs-1634R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C.