bs-1432R [Primary Antibody]
CD68 Polyclonal Antibody
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Host: Rabbit

Target Protein: CD68

Immunogen Range: 40-80/354

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 968

Swiss Prot: P34810

Source: KLH conjugated synthetic peptide derived from human CD68

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

Background: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

This image was generously provided by Amanda Brown, Ph.D. from Johns Hopkins University School of Medicine.Paraffin embedded human brain tissue labeled with Rabbit Anti-CD68 Polyclonal Antibody, Unconjugated (bs-1432R) at 1:50 followed by conjugation to the secondary antibody and Permanent Fast Red Quanto staining


Human U937 cells probed with CD68 Polyclonal Antibody, Unconjugated (bs-1432R) at 1:100 for 30 minutes followed by incubation with a PE Conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).