Target Protein: ZO-1
Immunogen Range: 1670-1720/1733
Entrez Gene: 7082
Swiss Prot: Q07157
Source: KLH conjugated synthetic peptide derived from human ZO-1
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Background: The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.