bs-1014R [Primary Antibody]
CD11b/c Polyclonal Antibody
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD11b, CD11c

Specificity: The immunogen of this product has partial sequence similarity to CD11d and may cross react.

Immunogen Range: 50-100/1152

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3684

Swiss Prot: P11215

Source: KLH conjugated synthetic peptide derived from human CD11b

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

Background: Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CD11b/Integrin αM/Integrin Alpha M Polyclonal Antibody, Unconjugated (bs-1014R) at 1:300, followed by conjugation to the secondary antibody and DAB staining


Human U937 cells probed with CD11b/c Polyclonal Antibody, Unconjugated (bs-1014R ) (0.2ug) for 30 minutes followed by incubation with a PE Conjugated secondary (green) for 30 minutes compared to control unstained cells (blue), secondary only (light blue) and isotype control (orange).