bs-0112M-A647 [Conjugated Primary Antibody]
Amyloid Precursor Protein Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
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Host: Mouse

Target Protein: Amyloid Precursor Protein

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 351

Source: KLH conjugated synthetic peptide derived from human Soluble APP-beta/alpha

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Conjugation: ALEXA FLUOR® 647

Excitation/ Emission: 650nm/665nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Rat
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.