bs-0050R-HRP [Conjugated Primary Antibody]
Caspase-9 Polyclonal Antibody, HRP Conjugated
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Host: Rabbit

Target Protein: Caspase-9

Immunogen Range: 280-330/416

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 842

Swiss Prot: P55211

Source: KLH conjugated synthetic peptide derived from human Caspase-9 subunit p35

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
IHC-P(1:200-400)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.