Target Protein: Nestin
Immunogen Range: 700-750/1893
Entrez Gene: 25491
Swiss Prot: P21263
Source: KLH conjugated synthetic peptide derived from rat Nestin
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Background: Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.